Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933715 | 0.95 | PDE4A (0.32) | FPR2FASNPDE4AKDM1ACYP3A4 | |
| SCHEMBL8933458 | 0.94 | FPR2 (0.32) | FPR2FASNPDE4AKDM1ACYP3A4 | |
| SCHEMBL8932672 | 0.94 | KDM1A (0.37) | FPR2FASNKDM1ACYP3A4CYP2C9 | |
| SCHEMBL8933706 | 0.90 | FPR2 (0.35) | FPR2FASNKDM1ACYP3A4CYP2C9 | |
| SCHEMBL8933505 | 0.90 | FPR2 (0.35) | FPR2FASNGABRA1GABRB2PDE4A | |
| SCHEMBL8959331 | 0.88 | FPR2 (0.34) | FPR2FASNGABRA1GABRB2PDE4A | |
| SCHEMBL8933538 | 0.87 | GABRA1 (0.40) | FPR2FASNGABRA1GABRB2PDE4A | |
| SCHEMBL8933682 | 0.85 | PDE4A (0.33) | FPR2FASNPDE4AKDM1ACYP3A4 | |
| SCHEMBL8933435 | 0.85 | FPR2 (0.33) | FPR2FASNGABRA1GABRB2PDE4A | |
| SCHEMBL8959265 | 0.85 | GABRA1 (0.38) | FPR2FASNGABRA1GABRB2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |