Pentachlorophenol

Pentachlorophenol

SCHEMBL8933797

CCOCC.OCCO.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.52
CYP2C9 P11712 4/20 0.52
HIF1A Q16665 3/20 0.52
HPGD P15428 2/20 0.52
HSD17B10 Q99714 2/20 0.52
MAPK1 P28482 1/20 0.52
TSHR P16473 3/20 0.48
ALDH1A1 P00352 2/20 0.48
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP2C19 P33261 1/20 0.39
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL11311505 0.85 TSHR (0.42) CYP1A2CYP2C9HIF1AHPGDHSD17B10
Pentachlorophenol SCHEMBL6840640 0.82 TSHR (0.71) CYP1A2CYP2C9HIF1AHPGDHSD17B10
Pentachlorophenol SCHEMBL18525333 0.79 TSHR (0.67) CYP1A2CYP2C9HIF1AHPGDHSD17B10
Perchlorobenzene SCHEMBL29156007 0.79 ALDH1A1 (0.35) ALDH1A1
Pentachlorophenol SCHEMBL8933811 0.79 TSHR (0.56) CYP1A2CYP2C9HIF1AHPGDHSD17B10
Ether SCHEMBL11081 0.76
Ether SCHEMBL188032 0.76 ALDH1A1 (0.62) HSD17B10MAPK1TSHRALDH1A1MEN1
Pentachlorophenol SCHEMBL4320916 0.76 MEN1 (0.57) CYP1A2CYP2C9HIF1AHPGDHSD17B10
Ether SCHEMBL8943279 0.76 ALDH1A1 (0.62) HSD17B10MAPK1TSHRALDH1A1MEN1
Ether SCHEMBL10536028 0.76 ALDH1A1 (0.62) HSD17B10MAPK1TSHRALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996026911-A1 EXPLOSIVES USING GLYCOL STILL BOTTOMS AN/GEL INTERNATIONAL (US) 1996-09-06 WO claimed
US-5531843-A INSTEAD OF FUEL OIL ICI EXPLOSIVES USA INC. 1996-07-02 US claimed