Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933932 | 0.91 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8934005 | 0.84 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL8933813 | 0.75 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8917393 | 0.73 | PTGS2 (0.59) | PTGS2PTGS1CYP1A2CYP2D6GRIA2 | |
| SCHEMBL8933979 | 0.72 | PTGS2 (0.52) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8933963 | 0.71 | PTGS2 (0.53) | PTGS2PTGS1CYP2D6CYP2C9 | |
| SCHEMBL8918689 | 0.70 | PTGS2 (0.51) | PTGS2PTGS1CYP1A2CYP2D6GRIA2 | |
| SCHEMBL8934137 | 0.70 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL8933933 | 0.69 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL6324134 | 0.68 | PTGS2 (0.54) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009304-A1 | BENZOPYRANOPYRAZOLYL DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-28 | — | — | WO | claimed |