Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 7/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934004 | 0.84 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL8933932 | 0.79 | PTGS2 (0.55) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL8937611 | 0.67 | PTGS2 (0.71) | PTGS2PTGS1F10 | |
| SCHEMBL8933813 | 0.64 | PTGS2 (0.55) | PTGS2PTGS1F10 | |
| SCHEMBL675236 | 0.61 | PTGS2 (0.60) | PTGS2PTGS1F10 | |
| SCHEMBL8758682 | 0.61 | LMNA (0.44) | PTGS2F10ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8691387 | 0.61 | PTGS2 (0.46) | PTGS2PTGS1F10 | |
| SCHEMBL8058061 | 0.60 | PTGS2 (0.59) | PTGS2PTGS1F10 | |
| SCHEMBL8933979 | 0.60 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL6324134 | 0.60 | PTGS2 (0.54) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009304-A1 | BENZOPYRANOPYRAZOLYL DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-28 | — | — | WO | claimed |