Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.51 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934138 | 1.00 | MME (0.51) | MMETGFBR1ACEALDH1A1KDM4E | |
| SCHEMBL19119032 | 0.80 | ECE1 (0.37) | MMETGFBR1ACEALDH1A1KDM4E | |
| SCHEMBL19107072 | 0.79 | ECE1 (0.36) | MMEACEALDH1A1KDM4EMAPT | |
| SCHEMBL5969049 | 0.77 | TGFBR1 (0.47) | MMETGFBR1ACEALDH1A1KDM4E | |
| SCHEMBL5969046 | 0.77 | TGFBR1 (0.47) | MMETGFBR1ACEALDH1A1KDM4E | |
| SCHEMBL9650023 | 0.77 | MME (0.58) | MMETGFBR1ACEALDH1A1KDM4E | |
| SCHEMBL13380098 | 0.77 | MME (0.58) | MMETGFBR1ACEALDH1A1KDM4E | |
| SCHEMBL14163011 | 0.77 | MME (0.58) | MMETGFBR1ACEALDH1A1KDM4E | |
| SCHEMBL16314051 | 0.75 | MME (0.56) | MMETGFBR1ACEALDH1A1THRB | |
| SCHEMBL12449198 | 0.74 | TSHR (0.46) | ALDH1A1MAPTBLMSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996032372-A1 | SERINE DERIVATIVES AND USE THEREOF IN COSMETICS | SOCHINAZ S.A. (FR) | 1996-10-17 | — | — | WO | disclosed |