Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934131 | 0.80 | MME (0.51) | ECE1ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL8934138 | 0.80 | MME (0.51) | ECE1ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL19107072 | 0.80 | ECE1 (0.36) | ECE1ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL19118987 | 0.78 | ACE (0.42) | ECE1ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL12449198 | 0.69 | TSHR (0.46) | ALDH1A1SMN1; SMN2MAPTBLMLMNA | |
| SCHEMBL13396864 | 0.69 | TSHR (0.46) | ALDH1A1SMN1; SMN2MAPTBLMLMNA | |
| SCHEMBL17323631 | 0.65 | ACE (0.46) | ECE1ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL19119035 | 0.65 | LMNA (0.46) | NAALAD2MMECASP3LMNA | |
| SCHEMBL1764859 | 0.64 | — | — | |
| SCHEMBL140867 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170196851-A1 | Novel Alpha-Hydroxy Carboxylic Acid And Derivatives And Other Gras- Based Prodrugs Of Opioids And Uses Thereof | THOTTATHIL JOHN K (US) | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196851-A1 | Novel Alpha-Hydroxy Carboxylic Acid And Derivatives And Other Gras- Based Prodrugs Of Opioids And Uses Thereof | OPRD1, OPRK1, OPRM1 | ECE1 2644/4885ACE 1971/4885FOLH1 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.