Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934518 | 0.85 | NPY1R (0.50) | SMN1; SMN2LMNAKDM4ETDP1NPY1R | |
| SCHEMBL8934514 | 0.83 | KMT2A (0.46) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL8934585 | 0.73 | NPY1R (0.52) | KDM4ENPY1RALDH1A1L3MBTL1KMT2A | |
| SCHEMBL8934620 | 0.70 | NPC1 (0.70) | RAB9ANPC1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL8934601 | 0.69 | SMN1; SMN2 (0.53) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8934533 | 0.69 | NPY1R (0.50) | SMN1; SMN2CYP1A2NPY1RALDH1A1POLB | |
| SCHEMBL8934504 | 0.67 | NPY1R (0.48) | SMN1; SMN2NPY1RALDH1A1POLBHPGD | |
| SCHEMBL12329335 | 0.64 | KDM4E (0.65) | RAB9ANPC1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9376686 | 0.63 | KDM4E (0.63) | RAB9ANPC1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL22529080 | 0.63 | KDM4E (0.63) | RAB9ANPC1SMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030350-A1 | AMIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |