Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 9/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934518 | 0.84 | NPY1R (0.50) | SMN1; SMN2LMNAAOC3NPY1RPOLB | |
| SCHEMBL8934585 | 0.82 | NPY1R (0.52) | AOC3NPY1RALDH1A1L3MBTL1KDM4E | |
| SCHEMBL8934597 | 0.74 | AOC3 (0.56) | AOC3NPY1RPOLBHPGDHSD17B10 | |
| SCHEMBL8934664 | 0.71 | AOC3 (0.65) | AOC3NPY1RPOLBHPGD | |
| SCHEMBL8934623 | 0.70 | AOC3 (0.55) | AOC3NPY1RPOLBHPGD | |
| SCHEMBL8934565 | 0.69 | AOC3 (0.70) | NPC1RAB9ALMNAAOC3NPY1R | |
| SCHEMBL8934598 | 0.69 | RAB9A (0.59) | SMN1; SMN2NPC1RAB9ALMNANPY1R | |
| SCHEMBL8934522 | 0.69 | POLB (0.52) | LMNAAOC3NPY1RPOLBALDH1A1 | |
| SCHEMBL9629092 | 0.68 | POLB (0.55) | SMN1; SMN2NPC1RAB9AAOC3NPY1R | |
| SCHEMBL8934514 | 0.68 | KMT2A (0.46) | SMN1; SMN2NPC1RAB9ALMNANPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030350-A1 | AMIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |