Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.54 |
| ▸ | TUBB | P07437 | 4/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643349 | 0.88 | TUBB4A (0.64) | ABCB1ABCG2KDM4ECYP3A4CYP2D6 | |
| SCHEMBL24994535 | 0.80 | ABCB1 (0.65) | ABCB1ABCG2KDM4EPOLBCYP3A4 | |
| SCHEMBL8934506 | 0.79 | TUBB4A (0.79) | KDM4EPOLBCYP3A4CYP2D6TUBB4A | |
| SCHEMBL2727281 | 0.79 | ABCG2 (0.83) | ABCB1ABCG2KDM4EPOLBCYP3A4 | |
| SCHEMBL4135376 | 0.78 | ABCB1 (0.67) | ABCB1ABCG2KDM4EPOLBCYP3A4 | |
| SCHEMBL31238141 | 0.77 | KDM4E (0.68) | ABCB1ABCG2KDM4EPOLBCYP3A4 | |
| SCHEMBL7230100 | 0.76 | TUBB4A (0.54) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| Calycopterin SCHEMBL2214965 | 0.76 | KDM4E (0.73) | ABCB1ABCG2KDM4EPOLBCYP3A4 | |
| Penduletin SCHEMBL30823992 | 0.75 | ABCB1 (1.00) | ABCB1ABCG2KDM4EPOLBCYP3A4 | |
| Penduletin SCHEMBL2217068 | 0.75 | ABCB1 (1.00) | ABCB1ABCG2KDM4EPOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |