Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MIF | P14174 | 1/20 | 0.67 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 6/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA3 | P07451 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31955669 | 1.00 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL7701763 | 0.84 | MAOB (0.72) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL29563608 | 0.84 | MAOB (0.72) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL852659 | 0.84 | MAOB (0.72) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL11126857 | 0.83 | MAOB (0.65) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL279860 | 0.80 | MAOB (0.77) | ALDH1A1KDM4EHPGDNPSR1MAOB | |
| SCHEMBL34468463 | 0.80 | MAOB (0.77) | ALDH1A1KDM4EHPGDNPSR1MAOB | |
| SCHEMBL29539474 | 0.80 | MAOB (0.77) | ALDH1A1KDM4EHPGDNPSR1MAOB | |
| SCHEMBL2554631 | 0.80 | MEN1 (1.00) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL10812793 | 0.79 | KMT2A (0.66) | ALDH1A1KDM4EHPGDNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |