Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.72 |
| ▸ | CA12 | O43570 | 2/20 | 0.72 |
| ▸ | CA9 | Q16790 | 2/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.72 |
| ▸ | CA3 | P07451 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | CA4 | P22748 | 1/20 | 0.72 |
| ▸ | CA6 | P23280 | 1/20 | 0.72 |
| ▸ | CA5A | P35218 | 1/20 | 0.72 |
| ▸ | CA7 | P43166 | 1/20 | 0.72 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.72 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | NT5E | P21589 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468463 | 0.85 | MAOB (0.77) | MAOBCA12CA9CA1CA3 | |
| SCHEMBL29539474 | 0.85 | MAOB (0.77) | MAOBCA12CA9CA1CA3 | |
| SCHEMBL279860 | 0.85 | MAOB (0.77) | MAOBCA12CA9CA1CA3 | |
| SCHEMBL11126857 | 0.84 | MAOB (0.65) | MAOBCA12CA9CA1CA3 | |
| SCHEMBL31955669 | 0.84 | ALDH1A1 (0.67) | MAOBCA12CA9CA1CA3 | |
| SCHEMBL8934632 | 0.84 | ALDH1A1 (0.67) | MAOBCA12CA9CA1CA3 | |
| Coumarin-3-Carboxylic Acid SCHEMBL29414591 | 0.84 | MAOB (1.00) | MAOBCA12CA9CA1CA3 | |
| Coumarin-3-Carboxylic Acid SCHEMBL93571 | 0.84 | MAOB (1.00) | MAOBCA12CA9CA1CA3 | |
| SCHEMBL31078224 | 0.84 | MAOB (0.74) | MAOBCA12CA9CA1CA3 | |
| SCHEMBL10703662 | 0.83 | FLT3 (0.71) | MAOBCA12CA9CA1CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164572-A | Coumarin-3-carboxamide derivative, preparation method thereof and application thereof in preparation of antitumor drugs | 广州医科大学 | 2023-12-05 | — | — | CN | claimed |
| CN-116375549-A | Method and system for synthesizing amide compound from nitrile compound | 深圳湾实验室 | 2023-07-04 | — | — | CN | claimed |
| CN-113461648-A | Coumarin 3-formamide neuraminidase inhibitor and preparation method and application thereof | 上海应用技术大学 | 2021-10-01 | — | — | CN | claimed |
| CN-105777689-A | Method for synthesizing 3-carbamoyl coumarin | 扬州大学 | 2016-07-20 | — | — | CN | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| EP-1377589-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-01-07 | — | — | EP | claimed |
| WO-2002062804-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2002-08-15 | — | — | WO | claimed |
| CN-117164572-B | Coumarin-3-carboxamide derivative, preparation method thereof and application thereof in preparation of antitumor drugs | 广州医科大学 | 2025-08-12 | — | — | CN | disclosed |
| CN-119684165-A | Cholesteric molecular clamp artificial receptor and method for detecting zinc ions in food by using same | 青海大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-119528760-A | Gel bipyrenyl fluorescent probe, preparation method thereof and application thereof in cadmium detection and removal | 浙江工业大学 | 2025-02-28 | — | — | CN | disclosed |
| WO-2025023073-A1 | PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, AND DISPLAY DEVICE PROVIDED THEREWITH | 東レ株式会社 | 2025-01-30 | — | — | WO | disclosed |
| WO-2025005007-A1 | PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, AND ELECTRONIC COMPONENT | 東レ株式会社 | 2025-01-02 | — | — | WO | disclosed |
| WO-2025005009-A1 | RESIN, PHOTOSENSITIVE COMPOSITIONS, CURED OBJECT, DISPLAY DEVICE, ELECTRONIC COMPONENT, AND METHOD FOR PRODUCING CURED OBJECT | 東レ株式会社 | 2025-01-02 | — | — | WO | disclosed |
| US-20020031795-A1 | Nitrocoumarins for detecting all micro-organisms | BIOMERIEUX S.A. (FR) | 2002-03-14 | — | — | US | disclosed |
| EP-1124986-A1 | NITROCOUMARINS FOR DETECTING ALL MICRO-ORGANISMS | Biomerieux S.A. (FR) | 2001-08-22 | — | — | EP | disclosed |
| EP-1027350-A1 | AMINOMETHYL-BENZO A]QUINOLIZIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATIONS FOR NEURODEGENRATIVE DISEASES | PIERRE FABRE MEDICAMENT (FR) | 2000-08-16 | — | — | EP | disclosed |
| WO-2000028073-A1 | NITROCOUMARINS FOR DETECTING ALL MICRO-ORGANISMS | BIOMERIEUX S.A. (FR) | 2000-05-18 | — | — | WO | disclosed |
| WO-1999021856-A1 | AMINOMETHYL-BENZO[A]QUINOLIZIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATIONS FOR NEURODEGENRATIVE DISEASES | PIERRE FABRE MEDICAMENT (FR) | 1999-05-06 | — | — | WO | disclosed |
| US-4196128-A | Process for the preparation of 3-cyanochromones | WARNER-LAMBERT COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4196128-A | Process for the preparation of 3-cyanochromones | WARNER-LAMBERT COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020031795-A1 | Nitrocoumarins for detecting all micro-organisms | CBR3, CYB5R3, CBR1 | MAOB 130/4885CA12 4339/4885CA9 3105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.