Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 6/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.51 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934573 | 0.82 | POLH (0.62) | ALDH1A1HPGDCYP3A4MAPTKDM4E | |
| SCHEMBL21822869 | 0.82 | MAPT (0.56) | ALDH1A1HPGDCYP3A4MAPTKDM4E | |
| SCHEMBL21823009 | 0.81 | MAPT (0.57) | ALDH1A1HPGDCYP3A4MAPTKDM4E | |
| SCHEMBL30660113 | 0.81 | MAPT (0.57) | ALDH1A1HPGDCYP3A4MAPTKDM4E | |
| 8,2'-Dimethoxyflavone SCHEMBL516353 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HPGDCYP3A4MAPTKDM4E | |
| SCHEMBL21822938 | 0.79 | MAPT (0.49) | ALDH1A1HPGDCYP3A4MAPTKDM4E | |
| SCHEMBL21822918 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HPGDCYP3A4MAPTKDM4E | |
| SCHEMBL21822985 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HPGDCYP3A4MAPTKDM4E | |
| SCHEMBL21822990 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HPGDCYP3A4MAPTKDM4E | |
| SCHEMBL21822809 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HPGDCYP3A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |