Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961542 | 0.97 | GABRA1 (0.35) | GABRA1GABRB2FFAR4DGAT1FPR2 | |
| SCHEMBL8934692 | 0.95 | FFAR4 (0.35) | GABRA1GABRB2FFAR4DGAT1OPRL1 | |
| SCHEMBL8934695 | 0.95 | FFAR4 (0.35) | GABRA1GABRB2FFAR4DGAT1FPR2 | |
| SCHEMBL8934709 | 0.94 | FFAR4 (0.34) | GABRA1GABRB2FFAR4DGAT1FPR2 | |
| SCHEMBL8934696 | 0.94 | FFAR4 (0.34) | GABRA1GABRB2FFAR4DGAT1FPR2 | |
| SCHEMBL8934732 | 0.94 | FFAR4 (0.34) | GABRA1GABRB2FFAR4DGAT1FPR2 | |
| SCHEMBL8934724 | 0.94 | FFAR4 (0.34) | GABRA1GABRB2FFAR4DGAT1FPR2 | |
| SCHEMBL8934687 | 0.93 | FFAR4 (0.37) | FFAR4DGAT1FPR2OPRL1GRIN1 | |
| SCHEMBL8961551 | 0.93 | FFAR4 (0.34) | GABRA1GABRB2FFAR4DGAT1OPRL1 | |
| SCHEMBL8961553 | 0.92 | FFAR4 (0.33) | GABRA1GABRB2FFAR4DGAT1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |