Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195354 | 0.81 | PRKACA (0.55) | SIRT2SIRT1MAPTTP53KMT2A | |
| SCHEMBL5557050 | 0.73 | GAA (0.51) | SIRT2GAAMGAMSIMGAM2 | |
| SCHEMBL17183509 | 0.71 | MGAM (0.54) | SIRT2SIRT1GAAMGAMSI | |
| SCHEMBL28759307 | 0.69 | TP53 (0.65) | MAPTALDH1A1TP53KDM4ETHRB | |
| SCHEMBL13043371 | 0.69 | SIRT2 (0.43) | SIRT2SIRT1GAAMGAMSI | |
| SCHEMBL1278514 | 0.67 | MGAM (0.48) | SIRT2SIRT1GAAMGAMSI | |
| SCHEMBL22864444 | 0.66 | ATM (0.48) | SIRT2GAAMGAMSIMGAM2 | |
| SCHEMBL19741644 | 0.66 | TP53 (0.43) | SIRT2SIRT1GAAMGAMSI | |
| SCHEMBL19741640 | 0.66 | TP53 (0.43) | SIRT2SIRT1GAAMGAMSI | |
| SCHEMBL1925658 | 0.66 | GAA (0.50) | SIRT2GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030048-A1 | PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-10-03 | — | — | WO | disclosed |