Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.68 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633201 | 0.78 | CYP19A1 (0.73) | CYP19A1CYP11B1CYP11B2QPCTPOLB | |
| SCHEMBL11494331 | 0.75 | CYP19A1 (0.68) | CYP19A1CYP11B1CYP11B2QPCTCYP17A1 | |
| SCHEMBL11492274 | 0.75 | CYP19A1 (0.63) | CYP19A1CYP11B1CYP11B2CACNA1BCYP17A1 | |
| SCHEMBL8893008 | 0.74 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11631856 | 0.74 | CYP19A1 (0.67) | CYP19A1CYP11B1CYP11B2QPCTPOLB | |
| SCHEMBL11750244 | 0.72 | CYP19A1 (0.63) | CYP19A1QPCTPOLB | |
| SCHEMBL8892342 | 0.72 | CYP19A1 (0.68) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11378017 | 0.72 | CYP19A1 (0.63) | CYP19A1CYP11B1CYP11B2QPCTPOLB | |
| SCHEMBL11753443 | 0.70 | CYP19A1 (0.56) | CYP19A1POLB | |
| SCHEMBL9374363 | 0.70 | CYP19A1 (0.60) | CYP19A1CYP11B1CYP11B2IDO1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | claimed |