SCHEMBL8934793

SCHEMBL8934793

[CH2]CCc1cn(CCCC)cn1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 10/20 0.45
CPB1 P15086 4/20 0.45
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
MTOR P42345 1/20 0.37
HRH4 Q9H3N8 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
TBXAS1 P24557 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8795862 0.93 CPB2 (0.44) CPB2CPB1CYP2C9TSHRCYP2C19
SCHEMBL16992726 0.87 CPB2 (0.48) CPB2CPB1CYP2C9TSHRCYP2C19
SCHEMBL25653942 0.86 CPB2 (0.47) CPB2CPB1CYP2C9TSHRCYP2C19
SCHEMBL9941754 0.86 CPB2 (0.47) CPB2CPB1CYP2C9TSHRCYP2C19
SCHEMBL4373193 0.84 CPB2 (0.46) CPB2CPB1CYP2C9TSHRCYP2C19
Bromide SCHEMBL16738793 0.83 CPB2 (0.45) CPB2CPB1CYP2C9TSHRCYP2C19
Bromide SCHEMBL16738786 0.83 CPB2 (0.45) CPB2CPB1CYP2C9TSHRCYP2C19
SCHEMBL28878999 0.81 CPB2 (0.47) CPB2CPB1CYP2C9TSHRCYP2C19
Bromide SCHEMBL16738791 0.80 CPB2 (0.48) CPB2CPB1TBXAS1ALDH1A1POLB
SCHEMBL9939620 0.79 CPB2 (0.46) CPB2CPB1TBXAS1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996029315-A2 IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 1996-09-26 WO claimed