Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PNP | P00491 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4006707 | 0.85 | MAPT (0.43) | MAPTALDH1A1KDM4EAPEX1RECQL | |
| SCHEMBL7970840 | 0.77 | PNP (0.40) | MAPTALDH1A1KDM4EAPEX1RECQL | |
| SCHEMBL8700858 | 0.77 | PARP1 (0.54) | MAPTALDH1A1KDM4EAPEX1RECQL | |
| SCHEMBL1663769 | 0.77 | PRKCI (0.56) | MAPTALDH1A1KDM4EAPEX1RECQL | |
| SCHEMBL3429702 | 0.76 | MAPT (0.43) | MAPTALDH1A1PNPPARP1HPGD | |
| SCHEMBL4565100 | 0.76 | BCL2 (0.44) | MAPTALDH1A1KDM4EAPEX1RECQL | |
| SCHEMBL22962863 | 0.76 | PARP1 (0.41) | MAPTALDH1A1PNPPARP1HPGD | |
| Bromide SCHEMBL2051879 | 0.74 | BCL2 (0.43) | MAPTALDH1A1KDM4EAPEX1RECQL | |
| SCHEMBL30882780 | 0.73 | PDE3B (0.44) | MAPTALDH1A1KDM4EPARP1HPGD | |
| SCHEMBL29258736 | 0.73 | PDE3B (0.44) | MAPTALDH1A1KDM4EPARP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029331-A1 | IMIDAZOQUINAZOLINES, DRUGS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION | DR. KARL THOMAE GMBH (DE) | 1996-09-26 | — | — | WO | disclosed |