Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME2 | P23368 | 5/20 | 0.57 |
| ▸ | ME1 | P48163 | 5/20 | 0.57 |
| ▸ | ME3 | Q16798 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9951192 | 0.98 | ME2 (0.56) | ME2ME1ME3SMN1; SMN2NPC1 | |
| SCHEMBL3673014 | 0.93 | SMN1; SMN2 (0.58) | ME2ME1ME3SMN1; SMN2NPC1 | |
| SCHEMBL13195578 | 0.85 | SMN1; SMN2 (0.64) | ME2ME1ME3SMN1; SMN2NPC1 | |
| SCHEMBL15985154 | 0.85 | SMN1; SMN2 (0.69) | ME2ME1ME3SMN1; SMN2NPC1 | |
| SCHEMBL8934905 | 0.85 | ME2 (0.57) | ME2ME1ME3NPC1POLB | |
| SCHEMBL24819373 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1HPGDPOLBMAPT | |
| SCHEMBL13858035 | 0.84 | SMN1; SMN2 (0.73) | SMN1; SMN2NPC1HPGDPOLBMAPT | |
| SCHEMBL8908929 | 0.84 | POLB (0.67) | ME2ME1ME3SMN1; SMN2NPC1 | |
| SCHEMBL4671683 | 0.84 | GFER (0.61) | ME2ME1ME3SMN1; SMN2NPC1 | |
| SCHEMBL27253358 | 0.84 | MEN1 (0.65) | SMN1; SMN2NPC1HPGDPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029088-A1 | NOVEL PIPERAZINE DERIVATIVES AS TYPE IL-1 RECEPTOR ANTAGONISTS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-09-26 | — | — | WO | disclosed |