Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ME2 | P23368 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934908 | 0.93 | ME2 (0.57) | SMN1; SMN2HPGDNPC1POLBMAPT | |
| SCHEMBL24819373 | 0.91 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDNPC1POLBMAPT | |
| SCHEMBL13858035 | 0.91 | SMN1; SMN2 (0.73) | SMN1; SMN2HPGDNPC1POLBMAPT | |
| Hydrochloric Acid SCHEMBL9951192 | 0.91 | ME2 (0.56) | SMN1; SMN2HPGDNPC1POLBMAPT | |
| SCHEMBL8908929 | 0.91 | POLB (0.67) | SMN1; SMN2HPGDNPC1POLBMAPT | |
| SCHEMBL4671683 | 0.91 | GFER (0.61) | SMN1; SMN2HPGDNPC1MEN1KMT2A | |
| SCHEMBL27253358 | 0.91 | MEN1 (0.65) | SMN1; SMN2HPGDNPC1POLBMEN1 | |
| SCHEMBL92506 | 0.90 | L3MBTL1 (0.63) | SMN1; SMN2HPGDPOLBMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL21681605 | 0.89 | POLB (0.65) | SMN1; SMN2HPGDNPC1POLBMAPT | |
| SCHEMBL9090627 | 0.89 | L3MBTL1 (0.61) | SMN1; SMN2HPGDPOLBMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139461-A2 | AMINO DERIVATIVES TO PREVENT NEPHROTOXICITY AND CANCER | Recepticon Aps (DK) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008113364-A2 | AMINO DERIVATIVES TO PREVENT NEPHROTOXICITY AND CANCER | RECEPTICON APS (DK) | 2008-09-25 | — | — | WO | disclosed |