Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934919 | 0.85 | ALDH1A1 (0.38) | MAPTL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL7770369 | 0.80 | PPARG (0.41) | METAP1PPARGLTB4RADORA3MAPT | |
| SCHEMBL8548149 | 0.79 | KMT2A (0.41) | PPARGADORA3MAPTL3MBTL1KDM4E | |
| SCHEMBL7770589 | 0.79 | PPARG (0.41) | METAP1PPARGLTB4RADORA3MAPT | |
| SCHEMBL8824325 | 0.78 | NPC1 (0.43) | METAP1ADORA3L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL31260432 | 0.73 | NPC1 (0.57) | METAP1ADORA3L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7454751 | 0.73 | NPC1 (0.57) | METAP1ADORA3L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL12655918 | 0.71 | ACACA (0.52) | METAP1PPARGLTB4RMAPTL3MBTL1 | |
| SCHEMBL7026949 | 0.71 | KDM4E (0.43) | ADORA3L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL8935762 | 0.71 | KMT2A (0.43) | PPARGADORA3MAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523402-A | COMPLEXING AGENTS FOR TARGETING RADIOACTIVE IMMUNOREAGENTS | STERLING WINTHROP INC. (US) | 1996-06-04 | — | — | US | disclosed |