Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934913 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL8002266 | 0.94 | LMNA (0.39) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL5676296 | 0.86 | AKR1B1 (0.37) | LMNAL3MBTL1AKR1B1 | |
| SCHEMBL5676584 | 0.86 | AKR1B1 (0.37) | LMNAL3MBTL1AKR1B1 | |
| SCHEMBL5834719 | 0.86 | AKR1B1 (0.37) | LMNAL3MBTL1AKR1B1 | |
| SCHEMBL27812284 | 0.85 | LMNA (0.39) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL27812286 | 0.85 | LMNA (0.39) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL1369560 | 0.84 | LMNA (0.46) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL3128140 | 0.84 | LMNA (0.46) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL3130561 | 0.84 | LMNA (0.46) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586687-A4 | TRANS-SIALIDASE AND METHODS OF USE AND MAKING THEREOF | UNIV NEW YORK (US) | 1996-04-17 | — | — | EP | claimed |
| EP-0586687-A1 | TRANS-SIALIDASE AND METHODS OF USE AND MAKING THEREOF | NEW YORK UNIVERSITY (US) | 1994-03-16 | — | — | EP | claimed |
| WO-1993018787-A1 | TRANS-SIALIDASE AND METHODS OF USE AND MAKING THEREOF | NEW YORK UNIVERSITY (US) | 1993-09-30 | — | — | WO | claimed |
| EP-0586687-A4 | TRANS-SIALIDASE AND METHODS OF USE AND MAKING THEREOF | UNIV NEW YORK (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0586687-A1 | TRANS-SIALIDASE AND METHODS OF USE AND MAKING THEREOF | NEW YORK UNIVERSITY (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1993018787-A1 | TRANS-SIALIDASE AND METHODS OF USE AND MAKING THEREOF | NEW YORK UNIVERSITY (US) | 1993-09-30 | — | — | WO | disclosed |