Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5676584 | 1.00 | AKR1B1 (0.37) | AKR1B1LMNAL3MBTL1 | |
| SCHEMBL5834719 | 1.00 | AKR1B1 (0.37) | AKR1B1LMNAL3MBTL1 | |
| SCHEMBL8002266 | 0.88 | LMNA (0.39) | AKR1B1LMNAL3MBTL1 | |
| SCHEMBL8934913 | 0.86 | LMNA (0.42) | AKR1B1LMNAL3MBTL1 | |
| SCHEMBL8934933 | 0.86 | LMNA (0.42) | AKR1B1LMNAL3MBTL1 | |
| SCHEMBL4654574 | 0.82 | — | — | |
| SCHEMBL541845 | 0.81 | AKR1B1 (0.30) | AKR1B1 | |
| SCHEMBL1001172 | 0.74 | LMNA (0.42) | AKR1B1LMNAL3MBTL1 | |
| SCHEMBL64935 | 0.74 | LMNA (0.42) | AKR1B1LMNAL3MBTL1 | |
| SCHEMBL616881 | 0.74 | LMNA (0.42) | AKR1B1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109175-B1 | saponin-like compounds isolated from Mandevilla species; comprising saponin oligosugar bound to a pregnane-3 beta -ol steroid portion; for decreasing spontaneous cell proliferation | UNIVERSITE DE SHERBROOKE (CA) | 2006-09-19 | — | — | US | disclosed |
| EP-1028734-B1 | USE OF SPECIFIC STEADY-STATE R-TYPE CALCIUM CHANNEL BLOCKERS | UNIV SHERBROOKE (CA) | 2006-02-22 | — | — | EP | disclosed |