SCHEMBL8934938

SCHEMBL8934938

CCCCCC1CCC(c2ccc(-c3ccc(-c4ccc(OC)c(F)c4F)cc3)c(F)c2F)CC1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 8/20 0.36
ALOX5AP P20292 2/20 0.35
FEN1 P39748 2/20 0.35
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
DPP4 P27487 1/20 0.33
CNR2 P34972 5/20 0.33
CNR1 P21554 2/20 0.33
ACHE P22303 1/20 0.31
HTR4 Q13639 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8935029 0.99 GAA (0.36) FPR2ALOX5APFEN1GAAMAPT
SCHEMBL8961952 0.97 FPR2 (0.34) FPR2ALOX5APFEN1GAAMAPT
SCHEMBL8962193 0.96 GAA (0.34) FPR2ALOX5APFEN1GAAMAPT
SCHEMBL19985495 0.94 MAPT (0.36) FPR2ALOX5APFEN1GAAMAPT
SCHEMBL19985518 0.93 GAA (0.38) FPR2GAAMAPTCNR2CNR1
SCHEMBL19985501 0.93 GAA (0.38) FPR2GAAMAPTCNR2CNR1
SCHEMBL19985516 0.93 GAA (0.38) FPR2GAAMAPTCNR2CNR1
SCHEMBL12736235 0.92 FEN1 (0.36) FPR2ALOX5APFEN1
SCHEMBL12740816 0.92 FEN1 (0.36) FPR2ALOX5APFEN1
SCHEMBL8934885 0.92 FPR2 (0.37) FPR2ALOX5APFEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed