SCHEMBL19985518

SCHEMBL19985518

CCCCCCCCC1CCC(c2ccc(-c3ccc(OC)c(F)c3F)c(F)c2F)CC1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
FPR2 P25090 5/20 0.35
CNR2 P34972 4/20 0.35
TRPV1 Q8NER1 1/20 0.34
LYPLA1 O75608 1/20 0.33
LYPLA2 O95372 1/20 0.33
ABHD16A O95870 1/20 0.33
CNR1 P21554 1/20 0.33
ACHE P22303 1/20 0.32
HTR4 Q13639 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19985501 1.00 GAA (0.38) GAAMAPTFPR2CNR2TRPV1
SCHEMBL19985516 1.00 GAA (0.38) GAAMAPTFPR2CNR2TRPV1
SCHEMBL19985495 0.99 MAPT (0.36) GAAMAPTFPR2CNR2TRPV1
SCHEMBL19985479 0.95 FPR2 (0.36) GAAMAPTFPR2CNR2ACHE
SCHEMBL8935029 0.94 GAA (0.36) GAAMAPTFPR2CNR2TRPV1
SCHEMBL12733617 0.94 MAPT (0.36) GAAMAPTCNR2TRPV1LYPLA1
SCHEMBL9405800 0.94 MAPT (0.36) GAAMAPTCNR2TRPV1LYPLA1
SCHEMBL19253467 0.94 MAPT (0.36) GAAMAPTCNR2TRPV1LYPLA1
SCHEMBL8934938 0.93 FPR2 (0.36) GAAMAPTFPR2CNR2CNR1
SCHEMBL19985213 0.92 MAPT (0.36) GAAMAPTCNR2TRPV1LYPLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed