Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY10 | O00398 | 16/20 | 0.52 |
| ▸ | GPR174 | Q9BXC1 | 13/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 6/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934963 | 0.89 | P2RY10 (0.60) | P2RY10GPR174LPAR5GPR34 | |
| SCHEMBL8935189 | 0.88 | P2RY10 (0.58) | P2RY10GPR174LPAR5GPR34 | |
| SCHEMBL8693317 | 0.85 | ITGB3 (0.43) | P2RY10GPR174ITGB3ITGA2B | |
| SCHEMBL560103 | 0.78 | ITGB3 (0.51) | P2RY10GPR174ITGB3ITGA2B | |
| SCHEMBL8692789 | 0.77 | ITGB3 (0.47) | P2RY10GPR174GPR34ITGB3ITGA2B | |
| SCHEMBL8697384 | 0.76 | P2RY10 (0.45) | P2RY10GPR174GPR34ITGB3ITGA2B | |
| SCHEMBL8934961 | 0.75 | LPAR5 (0.57) | P2RY10GPR174LPAR5GPR34 | |
| Serine SCHEMBL28305481 | 0.74 | LPAR5 (0.73) | P2RY10GPR174LPAR5GPR34 | |
| SCHEMBL28863962 | 0.73 | P2RY10 (0.87) | P2RY10GPR174LPAR5GPR34 | |
| SCHEMBL30778404 | 0.73 | P2RY10 (0.87) | P2RY10GPR174LPAR5GPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596024-A4 | LIPID CONJUGATES OF THERAPEUTIC PEPTIDES AND PROTEASE INHIBITORS. | VESTAR INC (US) | 1996-07-17 | — | — | EP | disclosed |
| EP-0596024-A1 | LIPID CONJUGATES OF THERAPEUTIC PEPTIDES AND PROTEASE INHIBITORS | NeXstar Pharmaceuticals, Inc. (US) | 1994-05-11 | — | — | EP | disclosed |
| WO-1993001828-A1 | LIPID CONJUGATES OF THERAPEUTIC PEPTIDES AND PROTEASE INHIBITORS | VICAL, INC. (US) | 1993-02-04 | — | — | WO | disclosed |