Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY10 | O00398 | 8/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | GPR174 | Q9BXC1 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692789 | 0.99 | ITGB3 (0.47) | P2RY10ITGB3ITGA2BGPR174PTPN1 | |
| SCHEMBL8693317 | 0.88 | ITGB3 (0.43) | P2RY10ITGB3ITGA2BGPR174PTPN1 | |
| SCHEMBL8935189 | 0.84 | P2RY10 (0.58) | P2RY10GPR174GPR34 | |
| SCHEMBL8934963 | 0.83 | P2RY10 (0.60) | P2RY10GPR174GPR34 | |
| SCHEMBL8957247 | 0.83 | PTPN1 (0.41) | ITGB3ITGA2BPTPN1PTPRC | |
| SCHEMBL8694073 | 0.78 | P2RY10 (0.60) | P2RY10GPR174GPR34 | |
| SCHEMBL560103 | 0.78 | ITGB3 (0.51) | P2RY10ITGB3ITGA2BGPR174PTPN1 | |
| SCHEMBL8692487 | 0.77 | P2RY10 (0.62) | P2RY10GPR174GPR34 | |
| SCHEMBL8934968 | 0.76 | P2RY10 (0.52) | P2RY10ITGB3ITGA2BGPR174GPR34 | |
| SCHEMBL4551608 | 0.75 | ITGB3 (0.74) | P2RY10ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554728-A | Lipid conjugates of therapeutic peptides and protease inhibitors | NEXSTAR PHARMACEUTICALS, INC. (US) | 1996-09-10 | — | — | US | claimed |
| EP-0596024-A4 | LIPID CONJUGATES OF THERAPEUTIC PEPTIDES AND PROTEASE INHIBITORS. | VESTAR INC (US) | 1996-07-17 | — | — | EP | claimed |
| EP-0596024-A1 | LIPID CONJUGATES OF THERAPEUTIC PEPTIDES AND PROTEASE INHIBITORS | NeXstar Pharmaceuticals, Inc. (US) | 1994-05-11 | — | — | EP | claimed |
| WO-1993001828-A1 | LIPID CONJUGATES OF THERAPEUTIC PEPTIDES AND PROTEASE INHIBITORS | VICAL, INC. (US) | 1993-02-04 | — | — | WO | claimed |
| US-5804552-A | COMPOUND CONSISTING OF TYROSINE OR HYDROXYPROLINE LINKED TO PHOSPHOLIPID BY PHOSPHOESTER BOND THROUGH HYDROXYL GROUP; CAPABLE OF CONJUGATION WITH THERAPEUTIC PEPTIDE | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-09-08 | — | — | US | disclosed |
| US-5554728-A | Lipid conjugates of therapeutic peptides and protease inhibitors | NEXSTAR PHARMACEUTICALS, INC. (US) | 1996-09-10 | — | — | US | disclosed |