Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 4/20 | 0.66 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.57 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.53 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.53 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13030814 | 1.00 | SGPL1 (0.66) | SGPL1PLA2G4APTPN1LPAR5LPAR3 | |
| SCHEMBL1273298 | 0.98 | SGPL1 (0.63) | SGPL1PLA2G4APTPN1LPAR5LPAR3 | |
| SCHEMBL861987 | 0.98 | SGPL1 (0.63) | SGPL1PLA2G4APTPN1LPAR5LPAR3 | |
| SCHEMBL8776459 | 0.91 | S1PR4 (0.59) | SGPL1LPAR5LPAR3LPAR1LPAR2 | |
| SCHEMBL31395563 | 0.85 | PGD (0.52) | SGPL1PLA2G4ALPAR5 | |
| SCHEMBL18286333 | 0.85 | SGPL1 (0.61) | SGPL1PLA2G4APTPN1LPAR5LPAR3 | |
| SCHEMBL195872 | 0.85 | SGPL1 (0.61) | SGPL1PLA2G4APTPN1LPAR5LPAR3 | |
| SCHEMBL43371 | 0.85 | SGPL1 (0.61) | SGPL1PLA2G4APTPN1LPAR5LPAR3 | |
| SCHEMBL9497069 | 0.84 | LPAR5 (0.68) | SGPL1PLA2G4ALPAR5LPAR3LPAR1 | |
| SCHEMBL10658463 | 0.84 | LPAR5 (0.68) | SGPL1PLA2G4ALPAR5LPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596024-A4 | LIPID CONJUGATES OF THERAPEUTIC PEPTIDES AND PROTEASE INHIBITORS. | VESTAR INC (US) | 1996-07-17 | — | — | EP | disclosed |
| EP-0596024-A1 | LIPID CONJUGATES OF THERAPEUTIC PEPTIDES AND PROTEASE INHIBITORS | NeXstar Pharmaceuticals, Inc. (US) | 1994-05-11 | — | — | EP | disclosed |
| WO-1993001828-A1 | LIPID CONJUGATES OF THERAPEUTIC PEPTIDES AND PROTEASE INHIBITORS | VICAL, INC. (US) | 1993-02-04 | — | — | WO | disclosed |