Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 4/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.59 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.59 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.59 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TSPO | P30536 | 1/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18286333 | 1.00 | SGPL1 (0.61) | SGPL1S1PR1S1PR3S1PR2S1PR5 | |
| SCHEMBL195872 | 1.00 | SGPL1 (0.61) | SGPL1S1PR1S1PR3S1PR2S1PR5 | |
| SCHEMBL20510812 | 0.91 | SGPL1 (0.58) | SGPL1S1PR1S1PR3S1PR2S1PR5 | |
| SCHEMBL29472620 | 0.91 | SGPL1 (0.58) | SGPL1S1PR1S1PR3S1PR2S1PR5 | |
| SCHEMBL17522136 | 0.91 | SGPL1 (0.58) | SGPL1S1PR1S1PR3S1PR2S1PR5 | |
| SCHEMBL8934971 | 0.85 | SGPL1 (0.66) | SGPL1PLA2G4ALPAR5PTPN1LPAR6 | |
| SCHEMBL13030814 | 0.85 | SGPL1 (0.66) | SGPL1PLA2G4ALPAR5PTPN1LPAR6 | |
| SCHEMBL861987 | 0.83 | SGPL1 (0.63) | SGPL1PLA2G4ALPAR5PTPN1LPAR6 | |
| SCHEMBL1273298 | 0.83 | SGPL1 (0.63) | SGPL1PLA2G4ALPAR5PTPN1LPAR6 | |
| SCHEMBL21428471 | 0.81 | S1PR2 (0.67) | SGPL1S1PR1S1PR3S1PR2S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189238-A1 | BIOMARKERS DISCRIMINATING PHENOTYPES OF X-ADRENOLEUKODYSTROPHY | INSTITUT D'INVESTIGACIÓ BIOMÈDICA DE BELLVITGE (ES) | 2024-09-19 | — | — | WO | claimed |
| US-20160206633-A1 | dhS1P AND USE OF SAME AS AN ANTICANCER THERAPEUTIC AND IMMUNOMODULATOR | THE PENN STATE RESEARCH FOUNDATION | 2016-07-21 | — | — | US | claimed |
| US-9274129-B2 | Methods and reagents for detecting bioactive lipids | LPATH, INC. (US) | 2016-03-01 | — | — | US | claimed |
| EP-2925301-A1 | PHOTODYNAMIC DHSIP ANTICANCER THERAPEUTIC AND IMMUNOMODULATOR | The Penn State Research Foundation (US) | 2015-10-07 | — | — | EP | claimed |
| EP-2399989-B1 | CULTURE MEDIUM AND METHOD FOR INDUCING DIFFERENTIATION INTO ADIPOCYTES | FUJIREBIO KK (JP) | 2015-04-08 | — | — | EP | claimed |
| US-20150031055-A1 | NOVEL BIOACTIVE LIPID DERIVATIVES, AND METHODS OF MAKING AND USING THE SAME | LPATH, INC. (US) | 2015-01-29 | — | — | US | claimed |
| US-20140205669-A1 | dhS1P AND USE OF SAME AS AN ANTICANCER THERAPEUTIC AND IMMUNOMODULATOR | THE PENN STATE RESEARCH FOUNDATION (US) | 2014-07-24 | — | — | US | claimed |
| WO-2014085461-A1 | PHOTODYNAMIC DHSIP ANTICANCER THERAPEUTIC AND IMMUNOMODULATOR | THE PENN STATE RESEARCH FOUNDATION (US) | 2014-06-05 | — | — | WO | claimed |
| EP-2027142-B1 | Diagnostic reagents and method for their use | LPATH INC (US) | 2013-03-06 | — | — | EP | claimed |
| JP-2009541215-A | — | — | 2009-11-26 | — | — | JP | claimed |
| EP-2035362-A4 | NOVEL BIOACTIVE LIPID DERIVATIVES, IMMUNE-DERIVED MOIETIES REACTIVE THERETO, AND METHODS OF MAKING AND USING THE SAME | LPATH INC (US) | 2009-08-26 | — | — | EP | claimed |
| EP-2027142-A4 | METHODS AND REAGENTS FOR DETECTING BIOACTIVE LIPIDS | LPATH INC (US) | 2009-08-19 | — | — | EP | claimed |
| EP-2035362-A2 | NOVEL BIOACTIVE LIPID DERIVATIVES, IMMUNE-DERIVED MOIETIES REACTIVE THERETO, AND METHODS OF MAKING AND USING THE SAME | Lpath, Inc. (US) | 2009-03-18 | — | — | EP | claimed |
| EP-2027142-A2 | METHODS AND REAGENTS FOR DETECTING BIOACTIVE LIPIDS | Lpath, Inc. (US) | 2009-02-25 | — | — | EP | claimed |
| US-20080090303-A1 | Methods and Reagents for Detecting Bioactive Lipids | APOLLO ENDOSURGERY, INC. | 2008-04-17 | — | — | US | claimed |
| US-20070281320-A1 | Novel Bioactive Lipid Derivatives, and Methods of Making and Using Same | INNOVATUS LIFE SCIENCES LENDING FUND I, LP | 2007-12-06 | — | — | US | claimed |
| WO-2007140431-A2 | NOVEL BIOACTIVE LIPID DERIVATIVES, IMMUNE-DERIVED MOIETIES REACTIVE THERETO, AND METHODS OF MAKING AND USING THE SAME | LPATH, INC. (US) | 2007-12-06 | — | — | WO | claimed |
| WO-2007140433-A2 | METHODS AND REAGENTS FOR DETECTING BIOACTIVE LIPIDS | LPATH, INC. (US) | 2007-12-06 | — | — | WO | claimed |
| US-7300764-B2 | Method for identifying agonists and antagonists of the GPR45-like/GPR63 receptor | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-11-27 | — | — | US | claimed |
| EP-1278850-B1 | EDG8 RECEPTOR, ITS PREPARATION AND USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-06-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140205669-A1 | dhS1P AND USE OF SAME AS AN ANTICANCER THERAPEUTIC AND IMMUNOMODULATOR | DHPS, CD47, DCLRE1A | SGPL1 14/4885S1PR1 236/4885S1PR3 479/4885 |
| US-20160206633-A1 | dhS1P AND USE OF SAME AS AN ANTICANCER THERAPEUTIC AND IMMUNOMODULATOR | DHPS, CD47, DCLRE1A | SGPL1 14/4885S1PR1 236/4885S1PR3 479/4885 |
| US-20070281320-A1 | Novel Bioactive Lipid Derivatives, and Methods of Making and Using Same | SGMS1, SGMS2, LPAR1 | SGPL1 36/4885S1PR1 11/4885S1PR3 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.