Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698809 | 0.98 | MEN1 (0.40) | MEN1KMT2AMAPTCCNB2CDK1 | |
| SCHEMBL6236362 | 0.88 | MEN1 (0.36) | MEN1KMT2AMAPTCCNB2CDK1 | |
| SCHEMBL9451016 | 0.84 | MEN1 (0.44) | MEN1KMT2AMAPTCCNB2CDK1 | |
| SCHEMBL9912110 | 0.83 | ALDH1A1 (0.44) | MEN1KMT2AMAPTCCNB2CDK1 | |
| SCHEMBL10932117 | 0.77 | MEN1 (0.63) | MEN1KMT2AMAPTCYP2C19CYP19A1 | |
| SCHEMBL9636744 | 0.74 | SMN1; SMN2 (0.54) | MEN1KMT2AMAPTCYP2C19CYP19A1 | |
| SCHEMBL8804519 | 0.74 | TAAR1 (0.43) | KMT2ACYP2C19ALDH1A1TDP1KDM4E | |
| SCHEMBL9451018 | 0.74 | MEN1 (0.41) | MEN1KMT2AMAPTCCNB2CDK1 | |
| SCHEMBL251443 | 0.73 | KDM1A (0.43) | MEN1KMT2AMAPTCCNB2CDK1 | |
| SCHEMBL1557131 | 0.73 | MAPT (0.50) | MEN1KMT2AMAPTCCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630261-A4 | NEW CYCLODEXTRINS AND NEW FORMULATED DRUGS. | AUSTRALIAN COMMERCIAL RESEARCH (AU) | 1996-11-06 | — | — | EP | disclosed |
| EP-0630261-A1 | NEW CYCLODEXTRINS AND NEW FORMULATED DRUGS | AUSTRALIAN COMMERCIAL RESEARCH & DEVELOPMENT LIMITED (AU) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993017711-A1 | NEW CYCLODEXTRINS AND NEW FORMULATED DRUGS | AUSTRALIAN COMMERCIAL RESEARCH & DEVELOPMENT LIMITED (AU) | 1993-09-16 | — | — | WO | disclosed |