Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912110 | 0.94 | ALDH1A1 (0.44) | MEN1KMT2AMAPTSLC18A3ALDH1A1 | |
| SCHEMBL698809 | 0.91 | MEN1 (0.40) | MEN1KMT2AMAPTSLC18A3ALDH1A1 | |
| SCHEMBL8935137 | 0.88 | MEN1 (0.38) | MEN1KMT2AMAPTSLC18A3ALDH1A1 | |
| SCHEMBL9451018 | 0.88 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL5851057 | 0.77 | MEN1 (0.34) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL2633867 | 0.77 | MAPK1 (0.47) | MEN1KMT2ASLC18A3ALDH1A1TP53 | |
| SCHEMBL511959 | 0.77 | KDM1A (0.40) | MEN1KMT2ACYP2C19CYP11B1CYP11B2 | |
| SCHEMBL3140395 | 0.77 | MAPT (0.51) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3083609 | 0.77 | RAB9A (0.44) | MEN1KMT2AMAPTSLC18A3ALDH1A1 | |
| SCHEMBL9451016 | 0.77 | MEN1 (0.44) | MEN1KMT2AMAPTPOLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011661-A1 | PHARMACEUTICAL AGENTS | UNIVERSITY COLLEGE LONDON (GB) | 2005-02-10 | — | — | WO | disclosed |