Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.62 |
| ▸ | GRM5 | P41594 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935244 | 0.88 | MAOB (0.69) | MAOBMAOASCN9AGRM5PARP10 | |
| SCHEMBL14323980 | 0.88 | MAOB (0.69) | MAOBMAOASCN9AGRM5PARP10 | |
| SCHEMBL993729 | 0.85 | GRM5 (0.59) | MAOBMAOASCN9AGRM5PARP10 | |
| Hydrochloric Acid SCHEMBL30001586 | 0.83 | MAOB (0.60) | MAOBMAOASCN9APARP10PPARA | |
| SCHEMBL993430 | 0.82 | GRM5 (0.55) | MAOBMAOASCN9AGRM5PARP10 | |
| SCHEMBL992642 | 0.81 | GRM5 (0.56) | MAOBMAOASCN9AGRM5PPARA | |
| SCHEMBL992772 | 0.81 | MAOB (0.60) | MAOBMAOASCN9AGRM5PPARA | |
| SCHEMBL993070 | 0.80 | MAOB (0.65) | MAOBMAOASCN9AGRM5PARP10 | |
| SCHEMBL994999 | 0.80 | MAOB (0.65) | MAOBMAOASCN9AGRM5PARP10 | |
| SCHEMBL993071 | 0.80 | MAOB (0.65) | MAOBMAOASCN9AGRM5PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933065-B2 | N-benzylamide substituted derivatives of 2-(acylamido)acetic acid and 2-(acylamido)propionic acids: potent neurological agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2015-01-13 | — | — | US | disclosed |
| US-20140342989-A1 | Novel N-Benzylamide Substituted Derivatives of 2-(Acylamido)acetic Acid and 2-(Acylamido)propionic Acids: Potent Neurological Agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-11-20 | — | — | US | disclosed |
| US-8829033-B2 | N-benzylamide substituted derivatives of 2-(acylamido)acetic acid and 2-(acylamido)propionic acids: potent neurological agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-09-09 | — | — | US | disclosed |
| US-20120232015-A1 | Novel N-Benzylamide Substituted Derivatives of 2-(Acylamido)acetic Acid and 2-(Acylamido)propionic Acids: Potent Neurological Agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-09-13 | — | — | US | disclosed |
| US-20110021482-A1 | Novel N-Benzylamide Substituted Derivatives of 2-(Acylamido)acetic Acid and 2-(Acylamido)propionic Acids: Potent Neurological Agents | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021482-A1 | Novel N-Benzylamide Substituted Derivatives of 2-(Acylamido)acetic Acid and 2-(Acylamido)propionic Acids: Potent Neurological Agents | NAAA, AADAC, GBA1 | MAOB 394/4885MAOA 252/4885SCN9A 135/4885 |
| US-20140342989-A1 | Novel N-Benzylamide Substituted Derivatives of 2-(Acylamido)acetic Acid and 2-(Acylamido)propionic Acids: Potent Neurological Agents | NAAA, AADAC, APEH | MAOB 312/4885MAOA 277/4885SCN9A 106/4885 |
| US-20120232015-A1 | Novel N-Benzylamide Substituted Derivatives of 2-(Acylamido)acetic Acid and 2-(Acylamido)propionic Acids: Potent Neurological Agents | NAAA, AADAC, APEH | MAOB 327/4885MAOA 274/4885SCN9A 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.