Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.54 |
| ▸ | GPR132 | Q9UNW8 | 6/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.46 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935335 | 0.85 | MAOB (0.53) | LTA4HDPP4 | |
| SCHEMBL31688840 | 0.82 | GPR132 (0.61) | ACACBGPR132CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8935407 | 0.80 | PARP10 (0.61) | ACACBGPR132LTA4HSMN1; SMN2MAPK1 | |
| SCHEMBL8935239 | 0.78 | MAOB (0.63) | — | |
| SCHEMBL7395944 | 0.78 | MAOB (0.59) | — | |
| SCHEMBL23488238 | 0.78 | PARP10 (0.68) | GPR132CYP19A1CYP11B1CYP11B2HTT | |
| SCHEMBL7337381 | 0.77 | ACACB (0.56) | ACACBGPR132CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7337394 | 0.77 | ACACB (0.56) | ACACBGPR132CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL28048524 | 0.77 | MAPK1 (0.64) | ACACBGPR132CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL2736161 | 0.76 | ACACB (0.60) | ACACBGPR132CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |