Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.56 |
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | GPR132 | Q9UNW8 | 5/20 | 0.50 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.43 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337381 | 1.00 | ACACB (0.56) | ACACBLTA4HGPR132MMP13PLG | |
| SCHEMBL25318441 | 0.87 | SLC7A5 (0.46) | LTA4HALDH1A1MAPTHTTKDM4E | |
| SCHEMBL30476014 | 0.87 | SLC7A5 (0.46) | LTA4HALDH1A1MAPTHTTKDM4E | |
| SCHEMBL7342884 | 0.86 | MAOB (0.52) | ACACBLTA4HMMP13ADAMTS4ALDH1A1 | |
| SCHEMBL7342898 | 0.86 | MAOB (0.52) | ACACBLTA4HMMP13ADAMTS4ALDH1A1 | |
| SCHEMBL7338844 | 0.86 | LTA4H (0.65) | LTA4HLAP3 | |
| SCHEMBL7339057 | 0.86 | LTA4H (0.65) | LTA4HLAP3 | |
| SCHEMBL7338836 | 0.86 | LTA4H (0.65) | LTA4HLAP3 | |
| SCHEMBL31688840 | 0.83 | GPR132 (0.61) | ACACBGPR132MMP13CYP19A1CYP11B1 | |
| SCHEMBL7375941 | 0.83 | ACACB (0.58) | ACACBLTA4HGPR132MMP13PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |