Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 4/20 | 0.60 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935452 | 0.86 | SCN9A (0.68) | CARM1PRMT6TP53MAOBLTA4H | |
| SCHEMBL966440 | 0.81 | SCN9A (0.75) | TP53GAAMAPTMAOBMAOA | |
| SCHEMBL2187391 | 0.81 | SCN9A (0.75) | TP53GAAMAPTMAOBMAOA | |
| SCHEMBL2186343 | 0.81 | SCN9A (0.75) | TP53GAAMAPTMAOBMAOA | |
| SCHEMBL8935279 | 0.81 | MAOB (0.60) | TP53GAAMAPTMAOBMAOA | |
| SCHEMBL2167250 | 0.80 | SCN9A (0.57) | TP53GAAMAPTMAOBMAOA | |
| SCHEMBL8935332 | 0.80 | GID4 (0.62) | CARM1PRMT6MAOBMAOACYP1A2 | |
| SCHEMBL2828868 | 0.80 | SCN9A (0.57) | TP53GAAMAPTMAOBMAOA | |
| SCHEMBL2167254 | 0.80 | SCN9A (0.57) | TP53GAAMAPTMAOBMAOA | |
| SCHEMBL8935297 | 0.79 | MAOB (0.59) | TP53GAAMAPTMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |