Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.68 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.62 |
| ▸ | CARM1 | Q86X55 | 8/20 | 0.57 |
| ▸ | PRMT6 | Q96LA8 | 8/20 | 0.57 |
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.54 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935290 | 0.86 | CARM1 (0.60) | SCN9ACARM1PRMT6MAOBLTA4H | |
| SCHEMBL8433722 | 0.83 | SCN9A (0.67) | SCN9ASCN3AMAOBPARP15PARP14 | |
| SCHEMBL8935432 | 0.81 | SCN3A (0.66) | SCN9ASCN3AMAOBPARP15PARP14 | |
| Ralfinamide SCHEMBL29379049 | 0.81 | SCN9A (1.00) | SCN9ASCN3AMAOBPARP15PARP14 | |
| Ralfinamide SCHEMBL962699 | 0.81 | SCN9A (1.00) | SCN9ASCN3AMAOBPARP15PARP14 | |
| Ralfinamide SCHEMBL67329 | 0.81 | SCN9A (1.00) | SCN9ASCN3AMAOBPARP15PARP14 | |
| SCHEMBL8755377 | 0.81 | CARM1 (0.54) | SCN9ACARM1PRMT6 | |
| Ralfinamide SCHEMBL67328 | 0.81 | SCN9A (1.00) | SCN9ASCN3AMAOBPARP15PARP14 | |
| SCHEMBL25259336 | 0.80 | SLC1A2 (0.60) | CARM1PRMT6 | |
| SCHEMBL25209028 | 0.80 | SLC1A2 (0.60) | CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |