Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935330 | 0.82 | EPHX2 (0.57) | MAPTALDH1A1SMN1; SMN2TSHRRECQL | |
| SCHEMBL8935415 | 0.81 | CARM1 (0.58) | PARP10ALOX15HPGDMAPTALDH1A1 | |
| SCHEMBL8935259 | 0.79 | CYP3A4 (0.60) | MAPTALDH1A1SMN1; SMN2TSHRRECQL | |
| SCHEMBL8935432 | 0.79 | SCN3A (0.66) | PARP10ALDH1A1SMN1; SMN2TSHRRECQL | |
| SCHEMBL8935279 | 0.78 | MAOB (0.60) | MAPTALDH1A1SMN1; SMN2TSHRRECQL | |
| SCHEMBL23291160 | 0.77 | HRH1 (0.58) | PARP10ALDH1A1SMN1; SMN2KDM4EMAOB | |
| SCHEMBL1680759 | 0.76 | PARP10 (0.60) | PARP10ALDH1A1SMN1; SMN2KDM4EMAOB | |
| SCHEMBL19380041 | 0.76 | TSHR (0.59) | PARP10ALOX15HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL1681064 | 0.76 | PARP10 (0.49) | PARP10ALOX15HPGDTDP1ALDH1A1 | |
| SCHEMBL7396633 | 0.76 | SCN9A (0.65) | PARP10MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |