Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935259 | 0.86 | CYP3A4 (0.60) | LMNANPC1MAPK1RAB9AALDH1A1 | |
| SCHEMBL8935404 | 0.82 | PARP10 (0.56) | LMNANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8935256 | 0.80 | POLB (0.59) | PKMLMNANPC1MAPK1RAB9A | |
| SCHEMBL8935382 | 0.80 | ALDH1A1 (0.46) | LMNANPC1RAB9AALDH1A1TSHR | |
| SCHEMBL8935238 | 0.79 | LTA4H (0.67) | ALDH1A1TSHRRECQLLTA4H | |
| SCHEMBL8935236 | 0.79 | MAOB (0.63) | — | |
| SCHEMBL8935322 | 0.79 | GID4 (0.71) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8935341 | 0.78 | LTA4H (0.53) | EPHX2F2LMNANPC1MAPK1 | |
| SCHEMBL8935432 | 0.78 | SCN3A (0.66) | LMNANPC1RAB9AALDH1A1TSHR | |
| SCHEMBL7350528 | 0.77 | ALDH1A1 (0.63) | LMNAALDH1A1TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |