Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.63 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396889 | 1.00 | SCN9A (0.63) | SCN9ASCN3AMAOBPARP15PARP14 | |
| SCHEMBL7396610 | 0.87 | MAOB (0.53) | SCN9AMAOBMMP9MMP8 | |
| SCHEMBL8935390 | 0.87 | MAOB (0.53) | SCN9AMAOBMMP9MMP8 | |
| SCHEMBL965367 | 0.87 | SCN9A (0.76) | SCN9ASCN3AMAOBPARP15PARP14 | |
| SCHEMBL1070090 | 0.86 | SCN9A (0.64) | SCN9ASCN3AMAOBPARP15PARP14 | |
| SCHEMBL9129379 | 0.86 | SCN9A (0.64) | SCN9ASCN3AMAOBPARP15PARP14 | |
| SCHEMBL963780 | 0.85 | SCN9A (0.73) | SCN9ASCN3AMAOBPARP15PARP14 | |
| SCHEMBL8935359 | 0.85 | MMP9 (0.56) | MAOBMMP9MMP8 | |
| SCHEMBL8935334 | 0.85 | MMP9 (0.56) | MAOBMMP9MMP8 | |
| SCHEMBL7395880 | 0.82 | MAOB (0.64) | SCN9AMAOBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |
| US-5391577-A | Active on central nervous system; antiepileptic agents | FARMITALIA CARLO ERBA S R L (IT) | 1995-02-21 | — | — | US | disclosed |
| US-5236957-A | Antiepileptic agents | FARMITALIA CARLO ERBA SRL (IT) | 1993-08-17 | — | — | US | disclosed |