Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935359 | 1.00 | MMP9 (0.56) | MMP9MMP8ALOX5BCHEMAOB | |
| SCHEMBL7395880 | 0.87 | MAOB (0.64) | MAOB | |
| SCHEMBL8935295 | 0.87 | MAOB (0.64) | MAOB | |
| SCHEMBL8935315 | 0.87 | ALOX5 (0.57) | ALOX5MAOB | |
| SCHEMBL8935390 | 0.85 | MAOB (0.53) | MMP9MMP8MAOB | |
| SCHEMBL7396610 | 0.85 | MAOB (0.53) | MMP9MMP8MAOB | |
| SCHEMBL7396889 | 0.85 | SCN9A (0.63) | MMP9MMP8MAOB | |
| SCHEMBL8935406 | 0.85 | SCN9A (0.63) | MMP9MMP8MAOB | |
| SCHEMBL8935316 | 0.85 | BCHE (0.57) | ALOX5BCHEMAOB | |
| SCHEMBL7394431 | 0.85 | BCHE (0.57) | ALOX5BCHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |