SCHEMBL8935446

SCHEMBL8935446

CCc1ncc(C2CN3CCC2C3)o1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8935428 0.81 CHRM2 (0.47) CHRM2
SCHEMBL10369506 0.81 CHRM2 (0.47) CHRM2
SCHEMBL8935502 0.73 CHRM2 (0.47) CHRM2
SCHEMBL9639034 0.73 CHRM2 (0.47) CHRM2
SCHEMBL24092044 0.70 PTGS1 (0.37)
SCHEMBL8935414 0.68 CHRM2 (0.45) CHRM2
SCHEMBL8935513 0.68 CHRM2 (0.45) CHRM2
SCHEMBL9458973 0.68
SCHEMBL13179146 0.66 ALDH1A1 (0.38)
SCHEMBL8935484 0.66 CHRM2 (0.54) CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541194-A PHARMACEUTICAL COMPOSTION USED TO TREAT DEMENTIA BEECHAM GROUP P.L.C. (GB) 1996-07-30 US claimed
US-5541194-A PHARMACEUTICAL COMPOSTION USED TO TREAT DEMENTIA BEECHAM GROUP P.L.C. (GB) 1996-07-30 US disclosed