Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935450 | 0.92 | CHRNB2 (0.49) | CHRM2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL8935428 | 0.72 | CHRM2 (0.47) | CHRM2CHRM1 | |
| SCHEMBL8935511 | 0.71 | CHRM2 (0.45) | CHRM2CHRNB2CHRNA4CHRNA7CHRM1 | |
| SCHEMBL8935513 | 0.71 | CHRM2 (0.45) | CHRM2CHRM1 | |
| SCHEMBL194766 | 0.70 | CHRM2 (1.00) | CHRM2CHRM1 | |
| SCHEMBL18998451 | 0.69 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL3154169 | 0.68 | — | — | |
| SCHEMBL8935414 | 0.68 | CHRM2 (0.45) | CHRM2CHRM1 | |
| SCHEMBL14112932 | 0.67 | CHRNB2 (0.81) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL8935446 | 0.66 | CHRM2 (0.40) | CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541194-A | PHARMACEUTICAL COMPOSTION USED TO TREAT DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1996-07-30 | — | — | US | claimed |
| US-5541194-A | PHARMACEUTICAL COMPOSTION USED TO TREAT DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1996-07-30 | — | — | US | disclosed |