Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PEPD | P12955 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8935476 | 0.98 | ALDH1A1 (0.45) | CHRNA7ALDH1A1GAAPEPDCHRM2 | |
| Hydrochloric Acid SCHEMBL8935473 | 0.89 | PEPD (0.43) | CHRNA7ALDH1A1PEPDCHRM2CHRM1 | |
| SCHEMBL15341643 | 0.80 | ALDH1A1 (0.46) | CHRNA7ALDH1A1GAACHRM2CHRM1 | |
| Bromide SCHEMBL9293836 | 0.78 | ALDH1A1 (0.41) | CHRNA7ALDH1A1GAACHRM2CHRM1 | |
| SCHEMBL261179 | 0.77 | CHRNA7 (0.50) | CHRNA7ALDH1A1GAACHRM2CHRM1 | |
| SCHEMBL260902 | 0.77 | CHRNA7 (0.50) | CHRNA7ALDH1A1GAACHRM2CHRM1 | |
| SCHEMBL260527 | 0.77 | CHRNA7 (0.50) | CHRNA7ALDH1A1GAACHRM2CHRM1 | |
| SCHEMBL8935448 | 0.77 | CHRM2 (0.41) | ALDH1A1GAACHRM2CHRM1MEN1 | |
| SCHEMBL28273440 | 0.76 | ALDH1A1 (0.49) | CHRNA7ALDH1A1GAACHRM2CHRM1 | |
| SCHEMBL8935442 | 0.76 | ALDH1A1 (0.40) | CHRNA7ALDH1A1GAACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541194-A | PHARMACEUTICAL COMPOSTION USED TO TREAT DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1996-07-30 | — | — | US | disclosed |