Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.84 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.84 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.84 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.84 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.84 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935488 | 0.91 | CHRM5 (1.00) | CHRM2CHRM1CHRM5CHRM3CHRM4 | |
| SCHEMBL8935513 | 0.71 | CHRM2 (0.45) | CHRM2CHRM1CHRM5CHRM3CHRM4 | |
| SCHEMBL8935511 | 0.71 | CHRM2 (0.45) | CHRM2CHRM1CHRM5CHRM3CHRM4 | |
| SCHEMBL8935414 | 0.71 | CHRM2 (0.45) | CHRM2CHRM1CHRM5CHRM3CHRM4 | |
| SCHEMBL9145005 | 0.67 | CHRM5 (0.51) | CHRM2CHRM1CHRM5CHRM3CHRM4 | |
| SCHEMBL10369506 | 0.66 | CHRM2 (0.47) | CHRM2CHRM1CHRM5CHRM3CHRM4 | |
| SCHEMBL8935484 | 0.66 | CHRM2 (0.54) | CHRM2CHRM1CHRNA7 | |
| SCHEMBL8935428 | 0.66 | CHRM2 (0.47) | CHRM2CHRM1 | |
| SCHEMBL7453827 | 0.64 | CHRM5 (0.49) | CHRM2CHRM1CHRM5CHRM3CHRM4 | |
| SCHEMBL21402172 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541194-A | PHARMACEUTICAL COMPOSTION USED TO TREAT DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1996-07-30 | — | — | US | claimed |
| EP-0322182-A2 | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1989-06-28 | — | — | EP | claimed |
| US-5541194-A | PHARMACEUTICAL COMPOSTION USED TO TREAT DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1996-07-30 | — | — | US | disclosed |
| EP-0322182-A2 | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1989-06-28 | — | — | EP | disclosed |