SCHEMBL893554

SCHEMBL893554

C1CCC2CCC(CC1)C2

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 1/20 0.33
HSD11B1 P28845 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30
NPC1 O15118 1/20 0.30
EPHX1 P07099 1/20 0.30
EPHX2 P34913 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL893375 1.00 ALDH1A1 (0.33) ALDH1A1HSD17B10HSD11B1CES2CES1
SCHEMBL20455768 1.00 ALDH1A1 (0.33) ALDH1A1HSD17B10HSD11B1CES2CES1
SCHEMBL892736 1.00 ALDH1A1 (0.33) ALDH1A1HSD17B10HSD11B1CES2CES1
SCHEMBL29217487 0.96 ALDH1A1 (0.36) ALDH1A1HSD17B10HSD11B1CES2CES1
SCHEMBL893232 0.96 ALDH1A1 (0.36) ALDH1A1HSD17B10HSD11B1CES2CES1
SCHEMBL65768 0.96
SCHEMBL6890483 0.96
SCHEMBL18239998 0.92 ALDH1A1 (0.33) ALDH1A1
SCHEMBL3957944 0.92 ALDH1A1 (0.33) ALDH1A1HSD17B10HSD11B1CES2CES1
SCHEMBL9307017 0.92 ALDH1A1 (0.33) ALDH1A1HSD17B10HSD11B1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4417180-A2 THERMO-ACTIVE COMPOSITE DENTAL COMPOSITION VOCO GmbH (DE) 2024-08-21 EP claimed
EP-3810064-B1 THERMOACTIVE DENTAL COMPOSITE COMPOSITION VOCO GMBH (DE) 2024-05-29 EP claimed
US-11944692-B2 Thermoactive dental composite composition VOCO GMBH (DE) 2024-04-02 US claimed
EP-3810064-A1 THERMOACTIVE DENTAL COMPOSITE COMPOSITION VOCO GmbH (DE) 2021-04-28 EP claimed
WO-2019243339-A1 THERMOACTIVE DENTAL COMPOSITE COMPOSITION VOCO GMBH (DE) 2019-12-26 WO claimed
US-20120184652-A1 CURABLE RESINS AND ARTICLES MADE THEREFROM DIGITALOPTICS CORPORATION EAST (US) 2012-07-19 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
US-6090853-A Fungicidally active carboxylic acid amides BASF AKTIENGESELLSCHAFT (DE) 2000-07-18 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
EP-0483167-A4 ZEOLITE SSZ-33 1993-03-17 EP claimed
EP-0483167-A1 ZEOLITE SSZ-33 CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1992-05-06 EP claimed
WO-1991000843-A1 ZEOLITE SSZ-33 CHEVRON RESEARCH COMPANY (US) 1991-01-24 WO claimed
EP-0171847-B1 LIQUID, CURABLE COATING COMPOSITION BASED ON A HYDROXYL GROUPS-CONTAINING ADDITION POLYMER AS BINDER AKZO N.V. (NL) 1988-06-01 EP claimed
US-12318459-B2 Thermoactive dental composite composition VOCO GMBH (DE) 2025-06-03 US disclosed
CN-116217566-B Anti-apoptosis protein BCL-2 inhibitor, pharmaceutical composition and application thereof 杭州和正医药有限公司 2025-05-23 CN disclosed
WO-1994029247-A1 SELECTIVE ALKYLATION OF DIAMONDOID COMPOUNDS WITH AN ALPHA-OLEFIN OVER A LEWIS ACID CATALYST MOBIL OIL CORPORATION (US) 1994-12-22 WO disclosed
US-5345020-A Aluminum halide or boron halide MOBIL OIL CORPORATION (US) 1994-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12318459-B2 Thermoactive dental composite composition PUF60, POLQ, F10 ALDH1A1 1414/4885HSD17B10 2755/4885HSD11B1 4389/4885
US-11944692-B2 Thermoactive dental composite composition PUF60, POLQ, F10 ALDH1A1 1414/4885HSD17B10 2755/4885HSD11B1 4389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.