Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307017 | 1.00 | ALDH1A1 (0.33) | ALDH1A1HSD17B10HSD11B1ADH1ACES2 | |
| SCHEMBL29217487 | 0.96 | ALDH1A1 (0.36) | ALDH1A1HSD17B10HSD11B1CES2CES1 | |
| SCHEMBL893232 | 0.96 | ALDH1A1 (0.36) | ALDH1A1HSD17B10HSD11B1CES2CES1 | |
| SCHEMBL358694 | 0.96 | ALDH1A1 (0.36) | ALDH1A1KMT2A | |
| SCHEMBL22129579 | 0.96 | ALDH1A1 (0.36) | ALDH1A1KMT2A | |
| SCHEMBL893554 | 0.92 | ALDH1A1 (0.33) | ALDH1A1HSD17B10HSD11B1CES2CES1 | |
| SCHEMBL893375 | 0.92 | ALDH1A1 (0.33) | ALDH1A1HSD17B10HSD11B1CES2CES1 | |
| SCHEMBL20455768 | 0.92 | ALDH1A1 (0.33) | ALDH1A1HSD17B10HSD11B1CES2CES1 | |
| SCHEMBL18239998 | 0.92 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL892736 | 0.92 | ALDH1A1 (0.33) | ALDH1A1HSD17B10HSD11B1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903614-A2 | NOVEL COMPOUNDS, THEIR SYNTHESIS AND THEIR USES | Sphaera Pharma Pte. Ltd (SG) | 2015-08-12 | — | — | EP | claimed |
| WO-2014054058-A2 | NOVEL COMPOUNDS, THEIR SYNTHESIS AND THEIR USES | SPHAERA PHARMA PVT. LTD. (SG) | 2014-04-10 | — | — | WO | claimed |
| US-20200339635-A1 | CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM S. AUREUS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2020-10-29 | — | — | US | disclosed |
| US-10723770-B2 | Crystal structure of the large ribosomal subunit from S. aureus | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2020-07-28 | — | — | US | disclosed |
| US-20200131232-A1 | CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM S. AUREUS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2020-04-30 | — | — | US | disclosed |
| US-10556934-B2 | Crystal structure of the large ribosomal subunit from S. aureus | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2020-02-11 | — | — | US | disclosed |
| EP-3250585-B1 | CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM S. AUREUS | YEDA RES & DEV (IL) | 2019-08-14 | — | — | EP | disclosed |
| US-20180009853-A1 | CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM S. AUREUS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2018-01-11 | — | — | US | disclosed |
| EP-3250585-A1 | CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM S. AUREUS | Yeda Research and Development Co., Ltd. (IL) | 2017-12-06 | — | — | EP | disclosed |
| WO-2016120868-A1 | CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM S. AUREUS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2016-08-04 | — | — | WO | disclosed |
| US-7618999-B2 | Process of obtaining taxosteroids and precursors thereof | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2009-11-17 | — | — | US | disclosed |
| US-7618999-B2 | Process of obtaining taxosteroids and precursors thereof | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2009-11-17 | — | — | US | disclosed |
| EP-2086958-A2 | SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF | Purdue Pharma LP (US) | 2009-08-12 | — | — | EP | disclosed |
| WO-2009095522-A1 | TAXANES, PRECURSORS THEREOF AND METHOD FOR OBTAINING SAME | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2009-08-06 | — | — | WO | disclosed |
| WO-2009027820-A2 | SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA L.P. (DE) | 2009-03-05 | — | — | WO | disclosed |
| US-20070185108-A1 | PROCESS OF OBTAINING TAXOSTEROIDS AND PRECURSORS THEREOF | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2007-08-09 | — | — | US | disclosed |
| US-20070185108-A1 | PROCESS OF OBTAINING TAXOSTEROIDS AND PRECURSORS THEREOF | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2007-08-09 | — | — | US | disclosed |
| EP-1642902-A2 | METHOD OF OBTAINING TAXOSTEROIDS AND PRECURSORS THEREOF | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2006-04-05 | — | — | EP | disclosed |
| EP-1642902-A2 | METHOD OF OBTAINING TAXOSTEROIDS AND PRECURSORS THEREOF | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2006-04-05 | — | — | EP | disclosed |
| EP-0122000-B1 | METHOD OF DETECTING TEMPERATURE IN AN OBJECT | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 1990-07-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10723770-B2 | Crystal structure of the large ribosomal subunit from S. aureus | MRPS27, MRPS35, MRPS23 | ALDH1A1 4855/4885HSD17B10 1795/4885HSD11B1 3748/4885 |
| US-20200339635-A1 | CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM S. AUREUS | MRPS27, MRPS35, MRPS23 | ALDH1A1 4855/4885HSD17B10 1795/4885HSD11B1 3748/4885 |
| US-20200131232-A1 | CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM S. AUREUS | MRPS27, MRPS35, MRPS23 | ALDH1A1 4855/4885HSD17B10 1795/4885HSD11B1 3748/4885 |
| US-20180009853-A1 | CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM S. AUREUS | MRPS27, MRPS35, MRPS23 | ALDH1A1 4855/4885HSD17B10 1795/4885HSD11B1 3748/4885 |
| US-10556934-B2 | Crystal structure of the large ribosomal subunit from S. aureus | MRPS27, MRPS35, MRPS23 | ALDH1A1 4855/4885HSD17B10 1795/4885HSD11B1 3748/4885 |
| US-20070185108-A1 | PROCESS OF OBTAINING TAXOSTEROIDS AND PRECURSORS THEREOF | CYP11B1, CYP11B2, HSD3B2 | ALDH1A1 1147/4885HSD17B10 45/4885HSD11B1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.