Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | PPARA | Q07869 | 10/20 | 0.47 |
| ▸ | PPARG | P37231 | 9/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615615 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2PPARAPPARGTDP1MEN1 | |
| SCHEMBL8935664 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2PPARAPPARGTDP1MEN1 | |
| SCHEMBL4820214 | 0.84 | SMN1; SMN2 (0.69) | SMN1; SMN2PPARAPPARGTDP1MEN1 | |
| SCHEMBL8431218 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2PPARAPPARGMAPTTSHR | |
| SCHEMBL14121845 | 0.81 | SMN1; SMN2 (0.74) | SMN1; SMN2PPARAPPARGTDP1MEN1 | |
| SCHEMBL7978358 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL11359371 | 0.80 | SMN1; SMN2 (0.73) | SMN1; SMN2PPARAPPARGTDP1MEN1 | |
| SCHEMBL421329 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL8935859 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL8935844 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417169-B2 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | ADRB2, ADRA2A, ADRA1A | SMN1; SMN2 4525/4885PPARA 752/4885PPARG 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.