Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 11/20 | 0.48 |
| ▸ | PPARG | P37231 | 10/20 | 0.44 |
| ▸ | PTGES | O14684 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935703 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARAPPARGPTGESALOX5 | |
| SCHEMBL11360035 | 0.88 | PPARG (0.51) | SMN1; SMN2PPARAPPARGPTGESALOX5 | |
| SCHEMBL3879629 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2PPARAPPARGTDP1 | |
| SCHEMBL8935641 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2PPARAPPARGTDP1 | |
| SCHEMBL4904732 | 0.86 | MAPT (0.42) | SMN1; SMN2PPARAPPARGPTGESALOX5 | |
| SCHEMBL11366338 | 0.84 | LMNA (0.45) | SMN1; SMN2POLBMAPTLMNARAB9A | |
| SCHEMBL31698014 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2PPARAPPARGPOLBLTB4R | |
| SCHEMBL28829280 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2PPARAPPARGPOLBLTB4R | |
| SCHEMBL28490552 | 0.84 | PPARG (0.49) | SMN1; SMN2PPARAPPARGPTGESALOX5 | |
| SCHEMBL8935678 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARAPPARGL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |