Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8755212 | 0.98 | CCR1 (0.39) | CCR1CCR8KDM4ETDP1L3MBTL1 | |
| SCHEMBL9073580 | 0.97 | IRAK4 (0.40) | CCR1CCR8KDM4ETDP1L3MBTL1 | |
| SCHEMBL522024 | 0.84 | HRH4 (0.46) | LOXL2HRH4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL15217633 | 0.83 | KDM4E (0.63) | CCR1CCR8KDM4ETDP1L3MBTL1 | |
| SCHEMBL1239870 | 0.82 | MEN1 (0.60) | KDM4ELMNAHSP90AA1IRAK4MEN1 | |
| Hydrochloric Acid SCHEMBL10753045 | 0.81 | GRIN2D (0.48) | LOXL2HRH4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28610171 | 0.81 | HRH4 (0.44) | LOXL2HRH4GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL26616811 | 0.81 | MEN1 (0.58) | KDM4ELMNAHSP90AA1IRAK4MEN1 | |
| SCHEMBL28199041 | 0.81 | HRH3 (0.50) | KDM4ETP53SMN1; SMN2IRAK4MEN1 | |
| Hydrochloric Acid SCHEMBL9297800 | 0.79 | FBP1 (0.50) | KDM4ELMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539117-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | GE HEALTHCARE AS (NO) | 1996-07-23 | — | — | US | disclosed |
| US-5350696-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | STERLING WINTHROP, INC. (US) | 1994-09-27 | — | — | US | disclosed |