Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | CCR1 | P32246 | 3/20 | 0.63 |
| ▸ | CCR5 | P51681 | 3/20 | 0.63 |
| ▸ | CCR8 | P51685 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | ALPL | P05186 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | ALPI | P09923 | 1/20 | 0.63 |
| ▸ | ALPG | P10696 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9073580 | 0.85 | IRAK4 (0.40) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| SCHEMBL8935818 | 0.83 | CCR1 (0.41) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| SCHEMBL18769070 | 0.82 | KDM4E (0.65) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| Hydrochloric Acid SCHEMBL8755212 | 0.81 | CCR1 (0.39) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| SCHEMBL13596181 | 0.81 | KDM4E (0.63) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| SCHEMBL20863011 | 0.81 | KDM4E (0.63) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| SCHEMBL2085837 | 0.81 | KDM4E (0.63) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| SCHEMBL2720567 | 0.81 | KDM4E (0.63) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| SCHEMBL14732968 | 0.81 | KDM4E (0.63) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| SCHEMBL313802 | 0.81 | KDM4E (0.63) | KDM4ETP53SMN1; SMN2LMNACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11067580-B2 | Compounds and methods for conjugation of biomolecules | Life Technologies Corporation (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200333351-A1 | Compounds and Methods for Conjugation of Biomolecules | Life Technologies Corporation | 2020-10-22 | — | — | US | disclosed |
| US-10648985-B2 | Compounds and methods for conjugation of biomolecules | Life Technologies Corporation (US) | 2020-05-12 | — | — | US | disclosed |
| US-20190079095-A1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | Life Technologies Corporation | 2019-03-14 | — | — | US | disclosed |
| EP-2966061-B1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | LIFE TECHNOLOGIES CORP (US) | 2017-05-03 | — | — | EP | disclosed |
| US-9566576-B2 | Metal complex catalysts and uses thereof | THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) | 2017-02-14 | — | — | US | disclosed |
| US-9566576-B2 | Metal complex catalysts and uses thereof | THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) | 2017-02-14 | — | — | US | disclosed |
| US-9566576-B2 | Metal complex catalysts and uses thereof | THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) | 2017-02-14 | — | — | US | disclosed |
| US-9233995-B2 | Quinazoline derivatives and quinazoline complex protein kinase inhibitor for inhibiting multiplication of tumor cells and preparation method thereof | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2016-01-12 | — | — | US | disclosed |
| US-20150072396-A1 | Compounds and Methods for Conjugation of Biomolecules | Life Technologies Corporation (US) | 2015-03-12 | — | — | US | disclosed |
| US-20150021197-A1 | NOVEL METAL COMPLEX CATALYSTS AND USES THEREOF | THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION | 2015-01-22 | — | — | US | disclosed |
| US-20150021197-A1 | NOVEL METAL COMPLEX CATALYSTS AND USES THEREOF | THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION | 2015-01-22 | — | — | US | disclosed |
| US-20150021197-A1 | NOVEL METAL COMPLEX CATALYSTS AND USES THEREOF | THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION | 2015-01-22 | — | — | US | disclosed |
| US-20130225811-A1 | QUINAZOLINE DERIVATIVES AND QUINAZOLINE COMPLEX PROTEIN KINASE INHIBITOR FOR INHIBITING MULTIPLICAITON OF TUMOR CELLS AND PREPARATION METHOD THEREOF | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCE (CN) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190079095-A1 | COMPOUNDS AND METHODS FOR CONJUGATION OF BIOMOLECULES | LIG3, LIG1, HLCS | KDM4E 2864/4885TP53 3624/4885SMN1; SMN2 3351/4885 |
| US-20200333351-A1 | Compounds and Methods for Conjugation of Biomolecules | LIG3, LIG1, HLCS | KDM4E 2864/4885TP53 3624/4885SMN1; SMN2 3351/4885 |
| US-11067580-B2 | Compounds and methods for conjugation of biomolecules | LIG3, LIG1, HLCS | KDM4E 2864/4885TP53 3624/4885SMN1; SMN2 3351/4885 |
| US-10648985-B2 | Compounds and methods for conjugation of biomolecules | LIG3, LIG1, HLCS | KDM4E 2864/4885TP53 3624/4885SMN1; SMN2 3351/4885 |
| US-20150072396-A1 | Compounds and Methods for Conjugation of Biomolecules | LIG3, LIG1, HLCS | KDM4E 2864/4885TP53 3624/4885SMN1; SMN2 3351/4885 |
| US-20130225811-A1 | QUINAZOLINE DERIVATIVES AND QUINAZOLINE COMPLEX PROTEIN KINASE INHIBITOR FOR INHIBITING MULTIPLICAITON OF TUMOR CELLS AND PREPARATION METHOD THEREOF | MAP3K21, MAP3K15, MAP3K14 | KDM4E 1544/4885TP53 735/4885SMN1; SMN2 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.