Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | PPARG | P37231 | 18/20 | 0.55 |
| ▸ | PPARA | Q07869 | 17/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433427 | 1.00 | SMN1; SMN2 (0.65) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL4820511 | 0.95 | SMN1; SMN2 (0.59) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL5405854 | 0.92 | SMN1; SMN2 (0.60) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL11550284 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL8935859 | 0.85 | SMN1; SMN2 (0.70) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL8935844 | 0.85 | SMN1; SMN2 (0.70) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL1171344 | 0.85 | SMN1; SMN2 (0.70) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL21991991 | 0.85 | PPARG (0.66) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL1745447 | 0.85 | PPARG (0.66) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL16242008 | 0.85 | PPARG (0.66) | SMN1; SMN2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108916-A | Racemic mixtures | RHONE-POULENC RORER, S.A. (FR) | 1992-04-28 | — | — | US | disclosed |
| EP-0407033-A2 | Lipase and isozymes, notably of Candida rugosa, and their use | RHONE-POULENC INC. (US) | 1991-01-09 | — | — | EP | disclosed |
| WO-1990015146-A1 | ENZYMES AND THEIR USE | RHONE-POULENC INC. (US) | 1990-12-13 | — | — | WO | disclosed |